Wednesday, 9 December 2015

Over a third of 60-70 year olds are battling the bulge


obesityScottish researchers claim that despite being a problem mainly associated among younger people, obesity is more widespread than first thought and over a third of 60 to 70-year-olds are now at a dangerous weight level.
The team involved in the new study also discovered that the amount of males aged 18 to 22 with a waist measurement in excess of 40 inches (102 cm), has doubled, increasing from 4.6% to 10.7%.
Meanwhile, the number of women in the same age bracket who have a waist size greater than 34.5 inches (88 cm) has almost tripled, increasing from 9.25% to 24.4%.
The team from the University of Glasgow analysed statistics from the Health Survey of England and the Scottish Health Survey, contrasting information relating to 1994 to 1996 against similar facts from 2008 to 2010.
They found that the total number of people with a body mass index (BMI) reading of more than 30 (I.e. classified as ‘obese’) had risen 5 to 15% on average, with an evident peak at age 60 to 70. Up to 38% were obese over both sexes.
The peak was seen at five to ten years later than what was observed during 1994 to 1996 for men, and but was no different for women.
Prevalence of BMI over 30 has doubled in young English men (to 10.7%) and tripled in young Scottish males (to 12.1%). Women fared worse though with 17.8% in England having a BMI of over 30 and 20.1% in Scotland.
Waistlines are clearly expanding at a fast rate, with researchers finding the percentage of people having a ‘large’ waist circumference – 102 cm/40 inches for men, 88 cm/34.5 inches for women – spiralling from 30% to 70% for men aged 80 to 85 and for women between the ages of 65 and 70.
It seems Scots are gripped in an even worse obesity crisis than their English counterparts as the prevalence of a large waist circumference increased fourfold to 12.7% in young men, and almost fivefold in women, to 28.2%.
Professor Mike Lean, whose research has been published in the International Journal of Obesity, commented: “People are growing fatter later in life, with waist sizes rising more persistently than BMI which may indicate increased loss of muscle mass in old age. Within the 14-year period of this study, we also are seeing more young people entering adult life already obese, and more older people have adverse body composition. The continuing rise of waist circumference in older age groups is evidence of continued body fat accumulation and redistribution into older age, which is a major public health concern. The proportion of people with a ‘normal’ BMI has dropped to only about 15 per cent of UK adults by the age of 65. This rather small proportion now includes unhealthy people who have illnesses that have caused weight loss or prevent weight gain, as well as those who are genuinely healthy and active. So older people with an apparently ‘healthy’ BMI are not all healthy.”
Professor Lean added: “The use of BMI alone as a measure for adiposity in this age group may be misleading and using waist circumference might be better for identifying adverse changes in body composition.”

Women are serial dieters in the battle of the bulge

There have been many diets that have become the new ‘craze’ over the last few years, with many people latching onto them in a desperate effort to drop those additional pounds. Diets such as the Atkins diet and the Weight Watcher’s diet with its points based system for all food, are just two of the main diets that spring to mind.
Men typically ‘hit the gym’ more often than resorting to strict dieting in their attempt to drop pounds, whereas it is thought that women will usually try more different methods in order to lose weight. This is backed up by a newly published survey that shows women have roughly tried 61 ‘diets’ by the time they are 45 years old. Remarkably, this equates to nearly 2 diets every year from the age of 16.
2,000 men and women were surveyed in the UK and it was found that over three-quarters had begun on a specific diet in the previous year. However, it was discovered that it was women who had dabbled in a considerable more different eating plans to try and lose weight.
However, there are now fears that this strict eating and calorie-counting may be rubbing off on children. 6/10 people quizzed admitted that their children had requested not to be given such healthy foods like fruit and vegetables and potatoes, with these children believing them to be bad for them. In addition, it seems some adults in the poll have an alarming lack of awareness in terms of their nutritional needs.  This is demonstrated in those aged under 26 who seemed to be unaware of the significance of calcium in their diet, despite the intake of it being vital to grow and maintain bones which carry on developing until you are approximately 30 years old. Some good sources for calcium include milk, leafy vegetables, fish and bread. Uneducated adults need to know the importance of calcium in keeping bones stronger later in life and helping to avoid the bone disease Osteoporosis. If children start copying their parents then they could be missing out on vital vitamins and minerals that are needed to help their body grow and become stronger.
TV doctor Hilary Jones commented on the latest findings, saying: “An average of 61 diets over an adult lifetime could mean an awful lot of people have cut a significant amount of calcium out of their diet over the years especially if they’ve been avoiding calcium-rich food groups on a regular basis. It seems the British obsession with dieting could be having a detrimental effect on our nutritional intake, as many people lose sight of what constitutes a healthy balanced diet. All breads contribute a range of essential nutrients from protein and calcium to iron and B group vitamins”.

How an obese sibling can leave the other at risk

Contrary to popular belief that a child’s obesity risk is more determined by their parent’s weight, it could be true that siblings have more of an impact on their brother’s or sister’s chance of becoming obese. This is according to the findings of a new study carried out in the US.
The research analysed information extracted from the national Family Habits Survey, finding that kids with obese siblings were five times more likely to be obese themselves, whereas children with obese parents were only twice as likely to also be obese.
“When you look at a two-child family, a child’s obesity status was more strongly related with their sibling than with their parent,” commented Mark Pachucki, a researcher with the Mongan Institute for Health Policy at Massachusetts General Hospital in Boston, and leader of the research.
According to the NHS, you are considered obese if you have a body mass index (BMI) reading of between 30 and 39.9. Becoming obese is basically the result of a calorie imbalance; gaining a large amount of weight from taking in more calories through your diet than you are burning from physical activity. However, the risk can increase through a combination of different factors such as genetics, the environment and lifestyle choices.
Previous research has found links between parent’s obesity and their children’s weight, but there has been little in the way of assessing the role of the weight of one sibling effecting the other’s obesity risk.
“This is really the first project to come out the bigger study, in which we are actually merging about 10 years of families’ food purchases with information about their health,” Pachucki said.
The research comprised of 1,948 families – 807 families with two children and 1,141 with just a single child. Eating and exercising were looked at, in addition to height and weight data to determine who was obese.
Around 12% of the only children could be classified as obese, with nearly a fifth not being physically active and over a third consuming fast food on two or more occasions each week.
A similar pattern emerged for those households with two children, but only 8% of the elder children could be classified as obese, in comparison to 12% of their younger brother or sister.
“We looked at one-child and two-child households, and in one-child households having an obese parent made a child more than twice as likely to be obese themselves,” Pachucki said.
Unsurprisingly, if the parents of an only child had a large intake of junk food, this led to a higher chance that the child would be obese, with a lesser risk if those children were involved in vigorous physical activity.
For two-child families, having an obese sibling led to a risk that was in excess of fives time of that than if the brother or sister wasn’t obese.
It was also found that if both children in a two-child family were the same gender, the elder sibling being obese resulted in an even heavier likelihood of the younger child being obese.
Girls with an older sister who was obese were 8 times more at risk of being obese themselves compared to girls with an older sister of a healthy weight, whilst boys with an older obese brother were a staggering 11 times more at risk.
“Parents are often very explicit models of behaviour; they do the food purchasing, and they control a lot of aspects of their children’s lives,” Pachucki said. “I was expecting there to be a stronger correlation with parents’ obesity, but I was surprised that the siblings were stronger.”

20% tax on sugary drinks could ease Britain’s obesity crisis


sugary drinksResearchers say that if a 20% tax was slapped onto all sugary drinks then this would help to bring down the total number of obese adults in the UK by an estimated 180,000.
Writing in the British Medical Journal, the researchers from Oxford and Reading argue that the 20% tax on Coca-Cola, Pepsi, Fanta and other sugar-sweetened drinks, would help to curb the worrying rise in sales of such drinks which they say is merely adding fuel to the fire of the nation’s obesity crisis.
The authors of the paper have spent time to calculate both the financial impact of introducing a 20% tax, and how much effect it could have in regards to trying to curtail the problem of obesity.
Dr Adam Briggs, lead study author from the Nuffield Department of Population Health at Oxford University, said their research has shown that taxing sugar-sweetened drinks “is a promising population measure”.
He commented: “Sugar-sweetened drinks are known to be bad for health and our research indicates that a 20% tax could result in a meaningful reduction in the number of obese adults in the UK. Such a tax is not going to solve obesity by itself, but we have shown it could be an effective public health measure and should be considered alongside other measures to tackle obesity in the UK.”
Dr Briggs and colleagues modelled the health effects of a 20% by using the information extracted from several separate surveys. These surveys had provided data on the trends of drink purchases, drinks consumption, and the prevalence of obesity throughout the UK.
They calculated that a 20% tax would equate to a 60p can of 330ml Coca-Cola now costing 72p, and help to cut the number of overweight adults in the UK by 0.9% (285,000 adults) and reduce the number of obese adults by 1.3% (180,000) adults. The tax would also result in roughly 40p being added to the cost of two-litre bottle.
The age group most effected would likely be those aged 16 to 29 the researchers say, as these typically consume a lot more sugary drinks in comparison to other age groups.
Because it is merely the over 30s who would be impacted by the introduction of the tax, this has led to some groups arguing that the tax would be misguided and simplistic, not having much of an impact on older people who could actually benefit most from losing weight.
Gavin Partington, director general of the British Soft Drinks Association, argued that soft drinks should not be blamed for Britain’s obesity problems.
He said: “There’s ample evidence to suggest that taxing soft drinks won’t curb obesity, not least because its causes are far more complex than this simplistic approach implies. Indeed, the latest official guidance from the National Institute for Health and Care Excellence points to the need to look at overall diet and lifestyle. Trying to blame one set of products is misguided, particularly when they comprise a mere 2% of calories in the average diet.”
In addition, Tom Sanders, professor of nutrition and dietetics at King’s College London, argued that the findings of the study were somewhat “naive”.
He said: “Most nutritionists agree it would be better to drink water than sugar-sweetened beverages. However, many consumers like sweet drinks and if they could not afford to buy sugary fizzy drinks they can always revert to drinking tea with added sugar as in the past. The cost of sugar-sweetened beverages is currently so low that any price increase would be so marginal that it would be unlikely to affect intake.”
However, the facts do not lie when it comes to fizzy drinks and the fact remains that a typical sugary drink still contains a shocking six to 15 teaspoons of sugary. Just one teaspoon of sugary works out at around 16 calories and 4g of sugar. On top of this, a regular consumption of the drinks has been linked to an increase in the risk of tooth decay and diabetes as well as obesity.
In fact, earlier this year doctors led calls for a tax on sugary drinks, in addition to other recommendations such as the number of fast food outlets close by to schools and colleges to be severely limited and a ban on junk food advertising before the watershed.

Modified mosquitoes to eradicate malaria?


malariaResearchers claim they have managed to genetically engineer mosquitoes which can resist the malaria infection, doing it in such a way that can nearly ensure the trait will rapidly spread through a population.
Californian researchers have utilised a cutting edge new technique known as gene editing, a technique that involves precise placement of new DNA to enable specific desired effects.
The gene editing technique they used – called CRISPR – allows the new trait to quickly spread and almost guaranteeing the new gene will be transmitted to new generations, limiting the transmission of malaria to humans.
“This opens up the real promise that this technique can be adapted for eliminating malaria,” said Anthony James of the University of California Irvine, who helped lead the study.
“We know the gene works. The mosquitoes we created are not the final brand, but we know this technology allows us to efficiently create large populations.”
The new breed that the researchers looked at were genetically modified Anopheles stephensi mosquitoes – of which normal versions are a common carrier of malaria within India and the Middle East – will not be able to either carry or transmit the deadly disease.
The scientists at the University of California modified the Anopheles stephensi mosquitoes’ DNA with a “resistance” gene, placed into the ‘code’ via a common “cut and paste” gene-altering method known as CRISPR/Cas9.
The technique has previously been utilised to look at the safety of using pig organs safe for human transplants, and produce an HIV-resistant immune system.
Specifically, an analysis was conducted on the mosquitoes’ DNA to try and transmit malaria-fighting antibodies for the particular type of malaria infection that impacts humans that infects humans - Plasmodium falciparum. For the modified mosquitoes, the malarial parasite is either killed off entirely, or stopped from forming into a strain that could be deadly to humans.
The Californian study includes an optimistic future plan to emit the modified mosquitoes into the wild and then the theory is these mosquitoes would give the anti-malarial genes to their offspring, thus generating a resistance to the parasite.
Amazingly, the DNA was successfully passed on to 99.5% of the mosquitoes’ offspring in the lab; genes only have a 50% chance of being passed on usually. In addition, a tracer gene was added to the malaria-resistant one, which would make the modified mosquitoes’ eyes become a fluorescent red in colour.
With further research and development, the team of scientists at the University of California are optimistic they will be able to eventually engineer an anti-malarial mosquito population, helping to eradicate a potentially deadly disease that afflicts millions of people around the globe each year.
Don’t forget, if you are wanting to escape the wet and miserable weather in the UK currently, and are travelling to particularly at-risk countries for malaria, The NHS Malaria Fit For Travel website offers advice about antimalarials such as Malarone and includes a map to show what other serious diseases are rife in certain regions.

World AIDS Day 2015 hopes to break the stigma about the disease


World AIDS DayAs a provider of numerous sexual health products and treatments, Medical Specialists® Pharmacy are proudly supporting World Aids Day 2015, which presents a fantastic opportunity for everyone around the world to unite in the huge fight against HIV and AIDS.
HIV (human immunodeficiency virus) attacks the immune system; our body’s natural defence mechanism against infections and disease. Health Protection Agency statistics from 2011 showed 95% of UK diagnoses stemmed from sexual contact, according to NHS Choices– failure to use a condom during sexual intercourse being the primary factor. Those who share infected needles, syringes or other drug paraphernalia are also at a high risk.
Following infection, symptoms can take between 2 to 6 weeks to show, including common flu symptoms such as fever, sore throat, tiredness, muscular pain and a body rash may also appear. Those that believe they might be at risk should not delay in being tested.
Delaying vital critical treatment can be fatal and somebody diagnosed at a late stage is actually 9 times more likely to die within 12 months of receiving their diagnosis compared to somebody who gets tested and diagnosed at an early stage.
If HIV is left untreated or insufficiently managed, HIV then develops into AIDS (acquired immune deficiency syndrome). At this stage the body is no longer able to fight off life-threatening infections due to the severe damage inflicted to the immune system.
According to the World Health Organisation, HIV is still a huge global public health issue. Even though the virus was only formally identified in 1984, so far HIV or AIDS has been responsible for the loss of more than 35 million lives.
Most people will have heard in the news recently that controversial Hollywood actor Charlie Sheen confirmed he was diagnosed with HIV back in 2011, putting an end to persistent rumours circulating around Hollywood. During an interview with NBC’s Today programme, the former 2 and a Half Men star said he sought medical help following consecutive nights of waking up soaking in sweat, and that his subsequent treatment has apparently rendered the virus almost “undetectable” in his system.
Sheen’s interview revealed he had paid “millions” to buy the silence of those aware of his condition, and only proved a reminder that the virus has not gone away and neither has the stigma about HIV and AIDS, with so many people reluctant to seek help initially, running the risk of receiving a diagnosis when it could be too late.
By the end of 2014, there were approximately 36.9 million people living with HIV and within the UK, an estimated 18,000 people of the 100,000 with HIV are unaware that they are living with the virus.
Every year on 1 December the National Aids Trust charity host World AIDS Day, using the day to boost people both discussing HIV and to help spread information about the virus. It is hoped that by more people talking about it, HIV will slowly lose the secrecy and stigma that surrounds it. More understanding and knowledge about HIV and AIDS, should hopefully result in less prejudice and better prevention methods.
Moreover, HIV is just one of many sexually transmitted diseases (STDs) in circulation. Medical Specialists® Pharmacy can provide STD treatment for many of the more common STDs such as chlamydia, gonorrhoea and genital herpes.
In addition, Medical Specialists® can provide almost 100% accurate pregnancy tests to be used in the privacy and comfort of the person’s own home, a wide variety of condoms to suit different preferences, emergency hormonal contraception (morning after pill), other contraceptive pills, and even a chlamydia test that can be used at home and posted off for a quick analysis and result, saving the time and embarrassment of having to personally attend a clinic for a check-up.
Please note that for every prescription medication mentioned which are provided by Medical Specialists®, all patients must first undergo an online consultation with one of the GMC-registered doctors at Medical Specialists®, or send in a private prescription by post, obtained by the patient’s own doctor.

Obesity may be passed on through the father’s sperm


spermDuring pregnancy – and maybe even whilst trying for a baby – most sensible women will usually decide to stop drinking and quit cigarettes in a boosted attempted to conceive, and then protect the health of the baby whilst in the womb.
However, new research has suggested that men may also need to watch what they eat and drink, following advice usually reserved for women, for an obesity risk may be passed on to children through the father’s sperm.
The Danish scientists involved in the new study discovered a series of genetic markers in the sperm of obese men, which have the chance of altering brain development and appetite control. It is interesting to note that these same changes were not present within the sperm of lean males.
Although more research is clearly needed in order to confirm such a theory is definitive, the tentative finding – if confirmed in much bigger studies – could lead to pressure on overweight men to lose weight and get in shape prior to starting a family, which may boost the chances of a healthier child.
“We don’t yet know if this is important. But if what we’ve found is transmitted to children and is doing something negative, it raises new questions about what do we need to do, and how long we need to do it before we conceive,” said Romain Barrès who led the study at the University of Copenhagen.
Past studies have demonstrated that obesity risk is strongly linked to both their inherited genes and their surrounding environment. The combination of factors leads to childhood BMI increasing line with parental weight, whilst previous analysis of twins found that as much of 70% of the differences between people’s fat mass can be attributed to DNA.
Researchers in the Danish study decide to look at the ‘epigenetic information’ found in the sperm of 10 obese men and 13 lean men. This information isn’t encoded in DNA, but is contained within other chemicals that work with DNA. One such example is the methyl molecules that can attach to specific genes and silence them.
Epigenetics can function in different ways, by changing the the protein that wraps DNA (adding or removing chemical “tags” that alter the structure of DNA), or via genetic molecules called small RNAs.
Reporting their findings in the journal Cell Metabolism, the researchers analysed the epigenetic marks on sperm from the two groups of men, formulating what they argue is a “distinct epigenome that characterises human obesity.” A few of the changes found change behavioural genes and eating “and could participate in predisposing the offspring to obesity”.
The researchers next decided to study the epigenetic information contained in the sperm of 6 morbidly obese men both prior to, and after undergoing gastric bypass surgery. A week after surgery, the epigenetic markers on 1509 genes had found to be changed in the sperm, increasing to 3,910 after a year. Over half also differed between obese and lean men.
It is uncertain if the epigenetic markers discovered are passed onto offspring, in addition to the extent of the effects if they indeed are passed on. Although a small proportion survives, the majority of such epigenetic information transmitted by sperm is eradicated during fertilisation. Barrès said added that the next step will be to conduct studies to investigate the sperm from obese fathers and IVF embryos they have donated after completing their families.
Wolf Reik, head of epigenetics at the Babraham Institute in Cambridge said that studies in animals have shown that changes in nutrition can alter the epigenetic markers carried by sperm. “It’s totally unknown what happens to these marks after fertilisation. In some ways the signals need to survive the global wipeout system, which is why it’s even more remarkable,” he said. “How strong the effects are in human populations is totally unknown. It’s impossible to tell at this point. That’s why the study is provocative, but much more needs to be done.”
Allan Pacey, professor of andrology at Sheffield University, commnted although the study was intriguing and could warrant further investigation, it is too early to say what the observations meant for human health. “Until we know more, would-be parents should just aim to be as healthy as possible at the time of conception and not be drawn to faddy diets or other activities in order to try and influence the health of their children in ways we don’t properly understand.”